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Antidiabetic (Oral Antidiabetics)

21 July 2009 2 Comments

antidiabetic-oral-antidiabeticsAn Antidiabetic (plural Antidiabetic) is a drug for the treatment of diabetes mellitus.

These include both tablets – Oral Antidiabetic agents – as well as various insulin preparations.

There are several groups with different oral Antidiabetic active.

Acarbose

Acarbose delays the glucose uptake from the intestine into the blood and helps, especially after carbohydrate meals the blood sugar low to keep.

Sulfonylurea

Sulfonylurea drugs, which stimulate and increase insulin secretion. Because of insulin resistance are thus often causes excessive insulin level. In most cases, the pancreas is constantly congested, after several years of decline in their performance. This “insulin deficiency due to exhaustion of the pancreas, secondary failure, may then usually only by insulin therapy.

Metformin

Metformin is currently the only approved substance from the group of Biguanide.

Insulin sensitizers

Insulin sensitizers improve the effect of insulin on insulin receptor.

Inkretin-mimetica and Dipeptidyl peptidase inhibitors

The Inkretin-mimetica and Dipeptidyl peptidase inhibitors based on the Inkretin effect. While the Inkretin-mimetica the effect of endogenous GLP-1 hormone simulate inhibit Dipeptidyl peptidase inhibitor whose degradation.

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